An Expert System for Optimizing Ultracentrifugation Runs

Martz, Philip R.; Heffron, Matt; Griffith, Owen Mitch

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Abstract:
The SpinPro™ Ultracentrifugation Expert System is a computer program that designs optimal ultracentrifugation procedures to satisfy the investigator's research requirements. SpinPro runs on the IBM PC/XT. Ultracentrifugation is a common method in the separation of biological materials. Its capabilities, however, are too often under-utilized. SpinPro addresses this problem by employing Artificial Intelligence (AI) techniques to design efficient and accurate ultracentrifugation procedures. To use SpinPro, the investigator describes the centrifugation problem in a question and answer dialogue. SpinPro then offers detailed advice on optimal and alternative procedures for performing the run. This advice results in cleaner and faster separations and improves the efficiency of the ultracentrifugation laboratory.